Efficacy of The Turkey Herpes virus-IBDV Vector Vaccine Against Recent Egyptian Very Virulent IBDV in Commercial Layers
نویسندگان
چکیده
منابع مشابه
A recombinant Newcastle disease virus (NDV) expressing VP2 protein of infectious bursal disease virus (IBDV) protects against NDV and IBDV.
Infectious bursal disease virus (IBDV) causes a highly immunosuppressive disease in chickens. Currently available, live IBDV vaccines can lead to generation of variant viruses. We have developed an alternative vaccine that will not create variant IBDV. By using the reverse genetics approach, we devised a recombinant Newcastle disease virus (NDV) vector from a commonly used vaccine strain LaSota...
متن کاملProtective efficacy of commercial live vaccines against very virulent infectious Bursal disease virus (vvIBDV) in Ghana
In spite of the intensive and varied vaccination procedures to control Infectious Bursa Disease (IBD), the emergence of a very virulent (vv) IBD pathotype in Ghana has led to high economic losses in the poultry industry. The potencies of two live intermediate IBD vaccine strains (TAD and Nobilis D78) and an intermediate-plus (hot) vaccine strain (228E) used in Ghana were evaluated by challengin...
متن کاملRecombinant chicken interleukin-7 as a potent adjuvant increases the immunogenicity and protection of inactivated infectious bursal disease vaccine
Our previous work showed that a plasmid-based chicken interleukin-7 (chIL-7) gene expression vector possessed potent adjuvant activity for a VP2 DNA vaccine against chicken infectious bursal disease virus (IBDV). Whether recombinant chIL-7 prepared in procaryotic expression system has the adjuvant activity for inactivated IBDV vaccine remains unknown. Here, we prepared recombinant chIL-7 using ...
متن کاملtransient expression of vp2 gene of very virulent ibdv in tobacco, alfalfa and lettuce leaves by agroinfiltration
vp2 protein is the major host protective immunogen of infectious bursal disease virus (ibdv) of chickens. plants are now gaining widespread acceptance as a general platform for the large scale production of recombinant proteins including vaccine, antibodies and pharmaceuticals. in present study vp2 gene of an iranian isolate of ibdv was cloned under strong plant expression promoter camv35s and ...
متن کاملDifferential gene expression in chicken primary B cells infected ex vivo with attenuated and very virulent strains of infectious bursal disease virus (IBDV).
Infectious bursal disease virus (IBDV) belongs to the family Birnaviridae and is economically important to the poultry industry worldwide. IBDV infects B cells in the bursa of Fabricius (BF), causing immunosuppression and morbidity in young chickens. In addition to strains that cause classical Gumboro disease, the so-called 'very virulent' (vv) strain, also in circulation, causes more severe di...
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ژورنال
عنوان ژورنال: Journal of Current Veterinary Research
سال: 2020
ISSN: 2636-4026
DOI: 10.21608/jcvr.2020.90223